Israeli Scientists Have Discovered the Key to the Fountain of Youth – Newsmax

After two decades of research, scientists at the Rambam Health Care Campus in Haifa and the Technion-Israel Institute of Technology have found a way to rejuvenate skin and human organs. successful study It was performed on experimental mice and just published in Science Advances from the American Association for the Advancement of Science.

according to Jerusalem PostThe study authors used an aged human skin graft on young mice and demonstrated that it is possible to make the skin and other organs young again by altering the molecular structure through all layers of the skin. Scientists from the Monasterium Laboratory in Germany and the University of Manchester called their study “Human Organ Regeneration by VEGF-A: Lessons from the Skin”.

Scientists transplanted aging human skin into young mice suffering from severe combined immunodeficiency disease (SCID) that affects both B and T lymphocytes. The scientists said this could rejuvenate transplanting living cells, tissues or organs from one type to another. . This process is accompanied by the growth of new blood vessels, re-pigmentation of the outer layer of skin called the epidermis, and a significant improvement in the biomarkers of aging, the paper says.

The scientists note that rather than viewing aging as a fatal disease, changing the view of aging as a “drugable and reprogrammable target, dissecting the main drivers of human organ aging and developing effective molecular strategies to prevent or even reverse it certainly constitutes one reason.” most basic tasks of biomedical research.”

Human skin is an ideal preclinical research model for investigating anti-aging methods because it is the first organ in the human body to clearly reflect changes in aging, such as changes in skin color and graying of hair.

The authors wrote: “While massive industrial efforts satisfy the age-old human desire to halt or reverse the aging skin phenotype, success on this frontier has remained moderate at best, and many claims of in vivo products (animal models) are typically rejuvenating.” Human skin is not supported by evidence.”

The promising study found that not only was the outer layer of human skin regenerated when SCID mice were vaccinated, but also all layers of the skin could become young again. To determine this, they used vascular endothelial growth factor A (VEGF-A) to evaluate the process, and additionally they found that even the number of new blood vessels in the transplanted skin increased.

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